Generic Samples

Related Articles Medication use as evidence for pharmacotherapeutics curriculum content. Am J Pharm Educ. 2009 Dec 17;73(8):148 Authors: Pitman SK, Sorofman B OBJECTIVE: To analyze the most common active ingredients in ambulatory prescription and nonprescription products to provide evidence for contemporary pharmacotherapeutics curricula development. METHODS: Content analysis was performed to code commonly dispensed prescription ingredients into American Hospital Formulary Service Pharmacologic-Therapeutic categories and commonly sold nonprescription products into self-care categories. This study used data from Drug Topics’ 2007 “top 200″ lists. RESULTS: For prescription drugs, when tallying the ingredients assigned to the AHFS categories “Cardiovascular Drugs” and “Central Nervous Systems Agents,” more than 50% of the total dispensed ingredients from the brand and generic top 200 lists were represented. For nonprescription products, over 75% of the commonly sold nonprescription products were categorized within 4 of the possible 11 self-care categories. CONCLUSIONS: This analysis provides a method for educators to use when collecting curricula-refining evidence and specific findings for evaluating therapeutics curricula. PMID: 20221341 [PubMed - in process]

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Medication use as evidence for pharmacotherapeutics curriculum content.

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A case of autoimmune hepatitis which worsened after switching from a brand name to a generic version of prednisolone.

Nippon Shokakibyo Gakkai Zasshi. 2009 Oct;106(10):1488-93

Authors: Kakizaki S, Suzuki H, Ichikawa T, Sato K, Takagi H, Mori M, Yuasa K

We recently encountered a case of autoimmune hepatitis whose symptoms worsened after switching from a brand name to a generic version of prednisolone. The patient was a 46-year-old woman. She was admitted because of elevation of alanine aminotransferase (ALT) levels during follow-up sessions. We diagnosed worsening of autoimmune hepatitis and increased the medication dose of prednisolone, which resulted in a quick normalization of serum ALT levels. When the prednisolone medication was switched from a brand name to a generic version, the serum ALT levels again increased. We concluded that switching from a brand name to generic version of the drug was one of reasons for the elevation in the serum ALT levels. Although most generic drugs are considered to be useful, it is important to carefully observe patients to confirm that an equivalent effect is obtained after switching from a brand name to a generic drug.

PMID: 19834296 [PubMed - in process]

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A case of autoimmune hepatitis which worsened after switching from a brand name to a generic version of prednisolone.